Long-term results of generalized periodontitis treatment among 2nd year medical university students with increased level of emotional sensitivity
Postgraduate student of Dentistry Department in Postgraduate Educational Institute, Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine
Introduction. In recent years, psychosocial factors, mental ex- haustion and stress have been considered by experts from WHO and the International Labor Organization as an important factor affecting the health of young people all over the world. The high level of psycho-emotional stress associated with information overload, the acceleration of life pace, unfavorable learning conditions, contributes to the increase in the prevalence of periodontal tissue diseases.
Aim. The purpose of the study was to evaluate the efficiency of long-term usage of the nootropic drug “Noofen” in complex treatment of generalized periodontitis among 2nd year medical university students with increased level of emotional sensitivity.
Material and methods. 70 students with initial-I stage generalized periodontitis and increased and high levels of emotional sensitivity were observed. Clinical indices PMA, BI, OHI-S and the level of MDA and SOD in saliva were detected.
Results. All data of clinical indices (PMA, BI, OHI-S) and prooxidant-antioxidant system state (MDA and SOD) was improved after treatment in both groups (p < 0.001), despite that I group results in a long-term, where advanced treatment was performed, was much more better than in II group (p < 0.001).
Conclusions. As a result of treatment we obtained significantly better results in group, where improved treatment was used. It is confirmed by long-term stabilization of clinical trials and biochemical parameters of oral fluid.
In recent years, psychosocial factors, mental exhaustion and stress have been considered by experts from WHO and the International Labor Organization as an important factor affecting the health and performance, motivation of learning and employment of young people all over the world (1).
Professional overload of emotional character in the absence of rational rest in most people leads to a state of chronic emotional stress. The high level of psycho-emotional stress associated with information overload, the acceleration of the pace of life, unfavorable learning and work conditions, contributes to the increase in the prevalence of periodontal tissue diseases. Psychological stress has a negative effect on immune response efficiency, which subsequently leads to disruption in periodontal tissues. The results of various factors influence on the periodontal tissue diseases occurrence indicate that not only stress but also anxiety is a determining factor in periodontal pathology development (2-6).
There are many methods of generalized periodontitis (GP) treatment, using drugs with high anti-inflammatory, antiseptic, antibacterial and antimicrobial effects on periodontal tissues. “Noofen” is one of the drugs that eliminates heightened emotional sensitivity, namely anxiety, and has a positive effect in GP treatment (7).
To evaluate the efficiency of long-term usage of the nootropic pill “Noofen” in complex treatment of generalized periodontitis among 2nd year medical university students with increased level of emotional sensitivity.
Material and methods
To evaluate the effectiveness of advanced complex treatment, we conducted clinical and laboratory examination and treatment of 70 2nd year medical university students with initial-I stage generalized periodontitis. All students, who were examinated, had increased and high levels of anxiety. Students were divided into two groups, depending on performed treatment: main or I group (35 people) and comparison or II group (35 people).
Patients in I group received advanced treatment, which included local treatment – mouthwash with solution “Oktenisept” and resorption of pill “Lizak”. For general treatment, patients in I group received nootropic pill “Noofen”. Patients in II group received conventional treatment according to the dental care protocol, which for local treatment included rinsing the mouth with 0.05% chlorhexidine solution and resorption of pill “Lisobact”. Patients in both groups received multivitamin complex “Vita-Supradin Active”.
Objective examination data, clinical indices of PMA (papillary-marginal-alveolar index), BI (bleeding index of gums), and Green-Vermillion index (OHI-S) were used to put initial-I stage of GP diagnosis. Danilevsky classification was used to put diagnosis of periodontal disease (8).
The assessment of oral cavity prooxidant-antioxidant system state was determined by the level of malondialdehyde (MDA) and superoxide dismutase (SOD) (9-11).
Clinical and laboratory examination of treatment in both groups were performed before and immediately after treatment, at 1 month, 6 months and 12 months.
Results and discussion
As a result of conducted treatment in both groups, a significant improvement of periodontal tissues condition was observed. Clinically, the gums became pale pink, tightened, bleeding and itching of the gums disappeared, and the depth of periodontal pockets decreased.
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