One of the most important problems in contemporary oncology is a low progress in reduction of mortality because of cancer. It has been recognized that there is a huge potential for improvements provided personalized – based on individual genotypes, medical management is applied. Studies of genotype-clinical correlations are the main goal of clinical genetics of cancer.

Enclosed please find a series of articles describing the latest progress in clinical genetics of cancers especially of the breast, colon, prostate, lung and thyroid gland. According to my opinion the most important of the latest advances are findings showing: