© Borgis - Postępy Nauk Medycznych 9/2008, s. 625-626
Due to the development of knowledge, more paediatric patients with chronic respiratory diseases are being referred for further medical care to adult specialists, for example CF patients suffering from this serious genetic disorder. Progress in its treatment in the final decade of the 20th century has resulted in increased life expectancy and a better quality of life.An exact molecular diagnosis of every patient will allow us to work out how to repair the CFTR protein defect caused by particular mutations, i.e. an individual therapeutic approach in specific classes, and even in single mutations of the CFTR gene. There are attempts at gene therapy of CF, but in the most advanced conditions the only efficient method of treatment is a lung transplant.
The next, very important issue is tuberculosis, still dangerous from a social point of view. The improvement of TB epidemiology in Poland, despite the application of modern bacteriology and molecular biology techniques, is making diagnosis more and more difficult.
Children suffering from TB are oligobacillous and the illness has only a few symptoms. Children often suffer from non-pulmonary localization, which makes the diagnosis even more difficult. That is why we consider it necessary to bear in mind the epidemiology and criteria of diagnosis of tuberculosis among children.
Respiratory system infections are still an important problem in children and diagnosis, treatment and prevention are still the primary concern of paediatricians. Children suffer more often from atypical pneumonias, and widely applied beta-lactam antibiotics are inefficient in these patients.
That is why it is so important to know how to diagnose and treat such conditions. In this light the review paper on atypical bacterial pneumonia and the case study of Chlamydophila pneumonia serve as an interesting reminder.
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