Ludzkie koronawirusy - autor: Krzysztof Pyrć z Zakładu Mikrobiologii, Wydział Biochemii, Biofizyki i Biotechnologii, Uniwersytet Jagielloński, Kraków

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© Borgis - New Medicine 1/2014, s. 33-38
Csilla Kata Karóczi1, Lászlónè Mèszáros1, Ádám Jakab1, Ágnes Korpos1, *Éva Kovács1, Tibor Gondos2
The effects of functional balance training on balance, functional mobility, muscle strength, aerobic endurance and quality of life among community-living elderly people: a controlled pilot study
1Department of Morphology and Physiology, Faculty of Health Science; Semmelweis University, Budapest, Hungary
Head of Department: prof. Gabriella Dörnyei, PhD
2Department of Clinical Studies; Semmelweis University, Budapest, Hungary
Head of Department: prof. Gyula Domján, PhD
Summary
Aim. The aim of this study was to investigate the effects of functional training on balance, functional mobility, muscle strength, aerobic endurance and quality of life among community-dwelling elderly people.
Material and methods. Eighteen women were in the exercise group taking part in functional training program for 25 weeks; the control group did not participate in any exercise program. The Fullerton test for balance, Timed Up and Go test for functional mobility, Five-Times-Sit-to-Stand Test for lower limb strength, Two-Minute-Step-in-Place Test for endurance and the quality of life were measured at baseline and after 25 weeks.
Results. After the training period in the exercise group the balance and the functional mobility improved more significantly than in the control group (p = 0.027; p = 0.0004, respectively). The quality of life showed a marginal significance (p = 0.083). In terms of lower limb muscle strength and aerobic endurance, the difference between the groups did not reach statistical significance (p = 0.276; p = 0.147).
Conclusion. This 25-week functional training improves balance, functional mobility, as well as quality of life among community-living elderly adults; however functional training exercises might require to be completed with more tailored strength exercises.
Clinical Rehabilitation Impact. Based on our results, functional training might be a promising exercise program for improving balance, functional mobility and quality of life for community-living elderly people.
Introduction
Safe balance is needed during the most activities of daily life (e.g., walking, sit-to-stand and sit down, transfer from one place to another, which are commonly referred to as functional mobility). The balance control is a complex process which requires the coordination of the sensory, musculoskeletal and nervous systems. Several parts of the nervous system including brain cortex and its projections, basal ganglia and other extrapyramidal components, cerebellum, as well as spinal cord take part in balance control. They are responsible for integrating the somatosensory, visual and vestibular information and then developing motor responses to maintain balance in changing environmental conditions (1). Furthermore, producing corrective movement for balance demands adequate musculoskeletal functions as well.
Studies examining age-related changes of balance control showed that sway during quiet stance begins to increase approximately at the age of fifty (2). Many of the age-related balance problems may stem from deterioration of sensory systems or neuromuscular system playing role in balance control (2).
With the increase of ageing population, improving of the elderly adults’ balance control is becoming more and more important.
In the rehabilitation of neurological diseases assotiated with injuries of neuromuscular and sensory systems functional training has been used with great success (3). Functional training consists of tasks which are important, meaningful, useful for people simulate their everyday activities (4). An animal study showed that practicing of meaningful tasks produced increased motor cortical representations than repetition of exercises without meaning (5). Since then, several clinical studies have proved that this therapeutic approach results in greater improvement which lasted longer in balance, functional mobility than usual stroke physiotherapy (6).
So far only three studies have evaluated the effects of functional training among ageing population but they focused on institutionalised elderly adults (7-9). To our knowledge, there is no functional balance training study conducted among community-living elderly adults.
Based on the results of previous studies, in agreement with the American College of Sports Medicines recommendations (10), we have developed a funtional balance training program consisting of exercises simulating everyday activities which required rotating head and trunk, weight transfer over different base of support. The exercises were accompanied by instructions reflecting selfcare, household or leisure-time activities which were meaningful and familiar to elderly people. The assumption underlying our exercise program was that practice and repetition of challenging task-oriented exercises accompanied by instructions recalling known situations might help imagine and perform the movement correctly, hence might help the process of motor learning.
The aim of present prospective, controlled study was to investigate the effects of a 25-week functional balance training program on static and dynamic balance, functional mobility, lower limb strength, aerobic endurance and quality of life among community-living elderly adults.
METHODS
Design
We conducted a parallel two-armed trial using an age and gender matched control group from March 2012 to September 2012. The study was conducted according to the 2008 revision of the 1975 Declaration of Helsinki (http://www.healthscience.net/resources/declaration-of-helsinki).
Study sample
Participants were recruited by advertisements in the local newspapers from the population of two districts in Budapest, Hungary. The volunteers’ general practitioners were informed in a letter about the aim of the study and and the extent of exertion required by the training. They had to decide if their patients were able to participate safely in the program. Potential participants were suitable for the experiment if they met the following criteria: aged 60 years or over, living in community, being able to move independently. Subjects were excluded if their general practitioner did not recommend the participation because of having progressive neurological or unstable cardiovascular diseases which would limit participation in the exercise program, if they had severe pain in lower limb in weight-bearing positions or if they had participated in an organized exercise program (sport or physiotherapy) recently or in the past 6-month period.
After eligibility was confirmed, eligible participants were matched by age (± 5 years) and gender with a control group of individuals who were recruited through advertisements in the local newspaper and posters displayed in senior centers.
After being explained the aim and procedure of the study, the subjects yielded consent to participation. They were aware of their right to withdraw from the study at any stage.
Intervention
Subjects in the experimental group participated in a group-based functional balance training program twice a week for 25 weeks. Training sessions were provided in a gymnasium situated in a local sports centre and were conducted by a physiotherapist with extensive geriatric clinical experience and with assistance of a physiotherapist student.
Each session lasted for 60 minutes starting with a five-to-ten-minute warming-up, including flexibility exercises and ended with a five-to-ten-minute stretching and breathing exercise program.
Exercises simulating everyday activities included sit-to-stand, sit down, turning, squatting, reaching to different directions, stepping up and down, stepping to different directions with weight transfer, standing and walking on narrow base of support, walking on uneven and soft surfaces, walking to different directions, walking avoiding obstacles, walking with changing directions. During the initial phase of training period (first 5-6 weeks), exercises were practiced separately, then they were combined. During the later phase of training period (after 6 weeks), exercises were combined with additional tasks including manipulation (e.g. holding and carring glass or tray, passing and throwing a ball) and conversation.
During the training safety was provided by allowing participants to lean on or hold on to a chair if needed. Instructions commenting the exercises were such as: „imagine that you take something off the shelf”; „imagine that you pick up something from the ground”; „imagine that you open a door; imagine that you carry a tray in your hand.
Subjects in the control group were asked to keep their usual daily activities unchanged during the 25-week study period. All participants were asked to maintain their medications and habitual diet.
Measurements
At baseline, the following data were obtained with a questionnaire: sociodemographic data (age, gender and marital status), physical and medical characteristics (weight, height and BMI was calculated, use of glasses, falling in the previous year, medications and medical history).
Dependent variables including static and dynamic balance, functional mobility, lower limb strength, aerobic endurance and health-related quality of life were assessed at baseline and at the end of the 25-week intervention period by two physiotherapist students.
The static and dynamic balance were measured with Fullerton test (11). This test includes 10 tasks simulating everyday life activities such as standing with feet together, eyes closed, reaching forward to an object, turning around, stepping up and over, tandem walk, standing on one leg, standing on foam rubber with eyes closed, two-foot jump, walking with head turns, reactive postural control. Each item was scored according to a five-point ordinal scale (from 0 to 4). Then scores were summed to produce a total index with a range from 0 to 40. A decreased total score showed poor balance of the subject. Fullerton test has excellent test-retest reliability (Correlation Coefficients = 0.96) and intrarater reliability (Correlation Coefficients = 0.97) (11).
The functional mobility was assessed with the Timed Up and Go (TUG) test (12). In TUG test, each participant was asked to stand up from a chair (approximate seat height of 46 cm), walk at a comfortable but secure speed to a cone on the floor 3 metres away and return to sit down on the chair. The time required was recorded. The digital stop-watch was stopped when he/she reached the sitting position with back against the backrest. The subject was allowed to wear their regular footwear and use the arms of the chair to get up. No physical assistance was given. The subject performed a trial once before testing. We calculated the average time of two consecutive performances and the participant was allowed to rest for 30 seconds between the trials, if needed. The TUG test has high interrater (Correlation Coefficients = 0.99) and intrarater (Correlation Coefficients = 0.99) reliability (12).
The lower limb strength was assessed with the Five-Times-Sit-to-Stand Test (13). Each participant was asked to stand up from a chair (approximate seat height of 46 cm) and sit down five times with arms crossed over chest. The time required was measured with a digital stop-watch which was started when the participant raised his/her legs and stopped when he/she reached the standing position after five repetitions. This test has good test-retest reliability (Correlation Coefficients = 0.89) and moderate intrarater reliability Correlation Coefficients = 0.64) (13).
The aerobic endurance was assessed with the Two-Minute-Step-in-Place Test which is an alternative to the Six Minutes Walking Test for ageing population with or without balance impairment. The participant was asked to march in place for two minutes lifting the knees to a predetermined height (midway between the patella and the iliac crest) as many times as possible. The participant was allowed to rest or hold onto the wall, if needed. The number of steps completed was counted (14).
The health-related quality of life was assessed using the EQ-5D (EuroQol) self-report questionnaire with which the respondent could classify his/her health according to five dimensions (mobility, self-care, usual activity, pain/discomfort, anxiety/depression) and rate his/her health on a visual Analogue Scale. The information derived from the EQ-5D dimensions was converted into a single summary index (EQ-5D index). The EQ-5D index ranged from 0 to 1, with higher value reflecting better self-experienced health-related quality of life (EQ-5D User Guide. www.eurowol.org)
Statistical Analysis

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Piśmiennictwo
1. Horak FB: Postural orientation and equilibrium: what do we need to know about neural control of balance to prevent falls? Age Ageing 2006; 35 Suppl: 2:ii7-ii11. 2. Lin SI, Woollacott MH, Jensen JL: Postural response in older adults with different levels of functional balance capacity. Aging Clin Exp Res 2004; 5: 369-374. 3. Rensink M, Schuurmans M, Lindeman E, Hafsteinsdóttir T: Task-oriented training in rehabilitation after stroke: systematic review. J Adv Nurs 2009; 65: 737-754. 4. Hubbard IJ, Parsons MW, Neilson C, Carey LM: Task-specific training: evidence for and translation to clinical practice. Occup Ther Int 2009; 16: 175-189. 5. Nudo RJ: Adaptive plasticity in motor cortex: implications for rehabilitation after brain injury. J Rehabil Med 2003; 41 Suppl: 7-10. 6. Langhammer B, Lindmark B: Functional exercise and physical fitness post stroke: the importance of exercise maintenance for motor control and physical fitness after stroke. Stroke Res Treat 2012; 2012: 864-835. 7. Tsaih PL, Shih YL, Hu MH: Low-intensity task-oriented exercise for ambulation-challenged residents in long-term care facilities: a randomized, controlled trial. Am J Phys Med Rehabil 2012; 9: 616-24. 8. Rugelj D: The effect of functional balance training in frail nursing home residents. Arch Gerontol Geriatr 2010; 50: 192-197. 9. de Bruin ED, Murer K: Effect of additional functional exercises on balance in elderly people. Clin Rehabil 2007; 21: 112-121. 10. Haskell WL, Lee IM, Pate RR et al.: American College of Sports Medicine; American Heart Association. Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Circulation 2007; 116: 1081-1093. 11. Rose DJ, Lucchese N, Wiersma LD: Development of a multidimensional balance scale for use with functionally independent older adults. Arch Phys Med Rehabil 2006; 87: 1478-1485. 12. Van Swearingen JM, Brach JS: Making geriatric assessment work: selecting useful measures. Phys Ther 2001; 81: 1233-1252. 13. Bohannon RW: Five-repetition sit-to-stand test: usefulness for older patients in a home-care setting. Percept Mot Skills 2011; 112: 803-806.
14. Różańska-Kirschke A, Kocur P, Wilk M, Dylewicz P: The Fullerton Fitness Test as an index of fitness in the elderly. Medical Rehabilitation 2006; 10: 9-16. 15. Verma R, Arya KN, Garg RK, Singh T: Task-oriented circuit class training program with motor imagery for gait rehabilitation in poststroke patients: a randomized controlled trial. Top Stroke Rehabil 2011; 18 Suppl 1: 620-632. 16. Outermans JC, van Peppen RP, Wittink H et al.: Effects of a high-intensity task-oriented training on gait performance early after stroke: a pilot study. Clin Rehabil 2010; 24: 979-987. 17. Laforge S, Vuillemin A, Bertrais S et al.: Association between leisure-time physical activity and health-related quality of life changes over time. Prev Med 2007; 44: 202-208. 18. Vuillemin A, Boini S, Bertrais S et al.: Leisure time physical activity and health-related quality of life. Prev Med 2005; 41: 562-569. 19. Eyigor S, Karapolat H, Durmaz B et al.: A randomized controlled trial of Turkish folklore dance on the physical performance, balance, depression and quality of life in older women. Arch Gerontol Geriatr 2009; 48: 84-88. 20. Tüzün S, Aktas I, Akarirmak U et al.: Yoga might be an alternative training for the quality of life and balance in postmenopausal osteoporosis. Eur J Phys Rehabil Med 2010; 46: 69-72.
otrzymano: 2014-01-09
zaakceptowano do druku: 2014-02-18

Adres do korespondencji:
*Éva Kovács
Department of Morphology and Physiology, Faculty of Health Science, Semmelweis University
H 1088 - Budapest, 17 Vas street, Hungary
tel.: +36 1 486-49-46
e-mail: kovacse@se-etk.hu

New Medicine 1/2014
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